Michel Gagnon on "PHP updated to version 5.3. What do I need to do?"

Hello,
It sounds like a weird question, but that's the first time I am faced with this. I just received a notice that, next week, my host will upgrade PHP on most servers from 5.2.16 to 5.3.16

I know that Zp works on PHP 5.2 and 5.3, so I don't expect any compatibility issue; however as PHP is upgraded on a database that is already installed, will I need to rerun Setup?

Thanks.